METHOD OF DETERMINING DEGREE OF INFLAMMATORY PROCESS EXPRESSION IN CASE OF KNEE JOINT OSTEOARTHROSIS Russian patent published in 2014 - IPC G01N33/48 G01N33/52 

FIELD: medicine.

SUBSTANCE: invention relates to medicine, namely to method of determining expression of inflammatory process in case of osteoarthrosis. Essence of method consists in the following: carried out is luminol-dependent iron-induced chemi-luminescence of model system, which has the following composition: 2.72 g of KH₂PO₄, 7.82 g of KCl, 1.5 g of sodium citrate C₆H₈O₇Na₃*5,5H₂O per 1 liter of distilled water, pH 7.45 with 0.2 ml of 10^-5 M luminol solution, after that, intensity of model system luminescence is determined in presence of synovial fluid before and after addition of synovial fluid. Degree of suppression of intensity of model system chemi-luminescence is calculated by formula. If its value is from 1.71 to 6.48%, high activity of inflammatory process is determined, if its value is from 6.49 to 21.55%, medium activity is determined, from 21.56 to 55.46 - small activity.

EFFECT: application of the method makes it possible to reduce time of determination and increases accuracy of assessment of inflammatory process degree in case of osteoarthrosis.

1 tbl, 1 dwg, 3 ex