PANCREATIC CANCER DIAGNOSTIC TECHNIQUE Russian patent published in 2014 - IPC G01N33/574 

FIELD: medicine.

SUBSTANCE: invention concerns a diagnostic agent for diagnosing pancreatic cancer and/or pancreatitis, involving α1→6 specific lectin, which is characterised by high affinity and high specificity to fucose. Fucose α1→6 specific lectin can have the effect on pathological haptoglobin being a part of the sample taken from a living body. The said lectin: (1) is recovered from basidium fungi; (2) has a molecular weight of 4000 to 40000 specified by SDS (sodium dodecyl sulphate) electrophoresis in polyacrylamide gel, and (3) has an affinity to the fucose α1→6 sugar chain 1.0×10⁴ M^-1 or more at a temperature of 25°C and (4) has an affinity constant of 1.0×10³ M^-1 or less at a temperature of 25°C for the long mannose sugar chain and/or glycolipid free from the fucose α1→6 sugar chain.

EFFECT: invention provides the accurate diagnosis of pancreatic cancer and/or pancreatitis.

3 cl, 13 dwg, 3 tbl