FIELD: medicine.
SUBSTANCE: what is presented is using a conjugate of a granulocytic colony-stimulating factor immobilised on low-molecular polyethylene glycol prepared by electron-beam synthesis nanotechnology - the exposure to an accelerated electron flow at an energy of 2.5 MeV, absorbed dose 2-10 kGy and collection rate 1.65 kGy/h as agents for the correction of remote consequences of spermatogenesis caused by the cytostatic exposure.
EFFECT: due to the penetration through the blood-testis barrier, the agent corrects disturbed spermatogenesis caused by the cytostatic exposure by the early stimulation of reticular regeneration processes in the testicular tissues in the whole and rapid spermatogonium population recovery; the agent is almost non-toxic.
3 tbl
Title | Year | Author | Number |
---|---|---|---|
REMEDY FOR DELAYED EFFECTS OF SPERMATOGENESIS DISORDERS CAUSED BY CYTOSTATIC EFFECT | 2019 |
|
RU2717240C1 |
METHOD OF CORRECTING, CAUSED BY CYTOSTATIC IMPACT | 2009 |
|
RU2406527C1 |
USE OF COMPLEX OF 9-PHENYL-2,3,4,5,6,7,8,9-OCTAHYDRO-1H-SELENOXANTHENE WITH β-CYCLODEXTRIN FOR CORRECTION OF SPERMATOGENESIS DISORDERS CAUSED BY CYTOTOXIC EFFECT | 2019 |
|
RU2782758C2 |
STIMULATOR OF REPARATIVE REGENERATION PROCESSES OF TESTICULAR TISSUE | 2019 |
|
RU2778238C2 |
USE OF PHARMACEUTICAL COMPOSITION OF β-CYCLODEXTRIN WITH 9-PHENYL-2,3,4,5,6,7,8,9-OCTAHYDRO-1H-SELENOXANTHENE FOR INCREASING/RESTORING LIBIDO | 2019 |
|
RU2782133C2 |
USE OF COMPLEX OF 9-PHENYL-2,3,4,5,6,7,8,9-OCTAHYDRO-1H-SELENOXANTHENE WITH β-CYCLODEXTRIN FOR TREATMENT OF PATHOZOOSPERMIA | 2019 |
|
RU2782140C2 |
BISAMIDE DERIVATIVE OF DICARBOXYLIC ACID AS AGENT FOR STIMULATING TISSUE REGENERATION AND RECOVERY OF DIMINISHED TISSUE FUNCTION | 2015 |
|
RU2647438C2 |
BISAMIDE DERIVATIVE OF DICARBOXYLIC ACID AS AGENT STIMULATING TISSUE REGENERATION AND RESTORATION OF REDUCED FUNCTIONS OF TISSUES | 2016 |
|
RU2727142C2 |
MEANS FOR PREVENTING AND CORRECTING SPERMATOGENESIS DISORDERS CAUSED BY CYTOSTATIC TREATMENT | 2006 |
|
RU2318529C1 |
METHOD FOR STIMULATION OF SPERMATOGENESIS | 2016 |
|
RU2653779C1 |
Authors
Dates
2014-12-10—Published
2013-04-04—Filed