FIELD: medicine.
SUBSTANCE: invention relates to medicine and can be used to stimulate the restoration of male fertility, including inborn or acquired impairment of the function of the spermatogenic testis tissue. A method for stimulating spermatogenesis involves injecting subalbugineal a suspension of multipotent mesenchymal stromal cells of human adipose tissue in a serum-free growth medium, deprived of xenogenic components, in an amount of 500–600 thousand cells contained in 400±100 mcl of suspension.
EFFECT: method provides a high degree of stimulation of spermatogenesis through activation of endogenous tissue-specific stem, progenitor cells and cells supporting spermatogenesis, with the provision of a prolonged effect up to 3 months or more after a single injection.
1 cl, 3 ex, 4 tbl, 4 dwg
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Authors
Dates
2018-05-14—Published
2016-12-26—Filed