FIELD: medicine.
SUBSTANCE: invention relates to medicine, in particular to andrology, and can be used for correction of spermatogenesis disorders caused by cytostatic effect. For this purpose preparation of recombinant human granulocytic colony-stimulating factor is introduced to laboratory animals (rats) in dose 100 mcg/kg 1 tiome per day for 5 days 1 month after cytostatic impact.
EFFECT: method allows to carry out efficient correction of spermatogenesis disorders caused by cytostatic damage due to stimulation of reparative processes of testicular tissue as a whole, resulting in formation of new sources of proliferative spermatogenesis pool.
2 tbl
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD FOR CORRECTION OF REMOTE CONSEQUENCES OF SPERMATOGENESIS CAUSED BY CYTOSTATIC EXPOSURE | 2013 |
|
RU2535002C2 |
| REMEDY FOR DELAYED EFFECTS OF SPERMATOGENESIS DISORDERS CAUSED BY CYTOSTATIC EFFECT | 2019 |
|
RU2717240C1 |
| USE OF COMPLEX OF 9-PHENYL-2,3,4,5,6,7,8,9-OCTAHYDRO-1H-SELENOXANTHENE WITH β-CYCLODEXTRIN FOR CORRECTION OF SPERMATOGENESIS DISORDERS CAUSED BY CYTOTOXIC EFFECT | 2019 |
|
RU2782758C2 |
| STIMULATOR OF REPARATIVE REGENERATION PROCESSES OF TESTICULAR TISSUE | 2019 |
|
RU2778238C2 |
| USE OF PHARMACEUTICAL COMPOSITION OF β-CYCLODEXTRIN WITH 9-PHENYL-2,3,4,5,6,7,8,9-OCTAHYDRO-1H-SELENOXANTHENE FOR INCREASING/RESTORING LIBIDO | 2019 |
|
RU2782133C2 |
| BISAMIDE DERIVATIVE OF DICARBOXYLIC ACID AS AGENT FOR STIMULATING TISSUE REGENERATION AND RECOVERY OF DIMINISHED TISSUE FUNCTION | 2015 |
|
RU2647438C2 |
| USE OF COMPLEX OF 9-PHENYL-2,3,4,5,6,7,8,9-OCTAHYDRO-1H-SELENOXANTHENE WITH β-CYCLODEXTRIN FOR TREATMENT OF PATHOZOOSPERMIA | 2019 |
|
RU2782140C2 |
| BISAMIDE DERIVATIVE OF DICARBOXYLIC ACID AS AGENT STIMULATING TISSUE REGENERATION AND RESTORATION OF REDUCED FUNCTIONS OF TISSUES | 2016 |
|
RU2727142C2 |
| METHOD FOR STIMULATION OF SPERMATOGENESIS | 2016 |
|
RU2653779C1 |
| METHOD FOR STIMULATION OF SPERMATOGENESIS | 2016 |
|
RU2652902C1 |
