METHOD OF INDIVIDUAL QUANTITATIVE ASSESSMENT OF RISK OF HYPERTENSION DEVELOPMENT Russian patent published in 2014 - IPC G01N33/48 

FIELD: medicine.

SUBSTANCE: invention relates to medicine, namely to therapy, cardiology, pathophysiology, biochemistry, pharmacology, and is intended for assessment of degree of hypertension development. Invention is based on discriminant analysis with application of a set of indices, coefficients and constants of displacement for particular category of patients, namely for smoking and non-smoking people. Value of discriminant function is calculated to determine presence or absence of hypertension. If value of discriminant function (d) is from -2 to 0, risk of hypertension development is estimated as low, if d is higher than 0, risk if hypertension development is estimated as increased in 100% of cases in smoking people and in 70% of cases in non-smoking people, and if d value is higher than 3, risk of hypertension development is estimated as high in 100% of cases both in smoking and non-smoking people. After that individual quantitative value of degree of risk of development or absence of hypertension in accordance with belonging to groups by smoking is determined: absence of hypertension is determined by formula RE=1/(1+EXP(d))*100%, where (d) is value of discriminant function, and presence of hypertension is determined as 100-RE(%). Application of method will make it possible to carry out individual assessment of hypertension development at early stages, to monitor health condition to people, who are redisposed to disease, as well as to use method in assessment of treatment efficiency in patients with achieved target levels of arterial pressure. Invention sensitivity constitutes 98.5% for smoking people and 88.6% for non-smoking people.

EFFECT: quality of diagnostics constitutes 96,2% for smoking people and 86,6% for non-smoking people.

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