FIELD: medicine.
SUBSTANCE: as active ingredients, a formulation contains fenoterol hydrobromide and ipratropium bromide monohydrate; the excipients are absolute ethanol, triethylcitrate, propellant 1,1,1,4 tetrafluoroethane (HFA-134a) and/or 1,1,1,2,3,3,3-heptafluoropropane (HFA-227ea) and a pharmaceutically acceptable acid specified in hydrochloric, orthophosphoric and citric acids.
EFFECT: increasing the respirable fraction and obtaining an optimised particle release profile.
2 dwg, 6 ex
Title | Year | Author | Number |
---|---|---|---|
AEROSOL PREPARATION OF IPRATROPIUM BROMIDE FOR TREATING RESPIRATORY DISEASES | 2013 |
|
RU2519653C1 |
AEROSOL PREPARATION BASED ON FENOTEROL HYDROBROMIDE FOR TREATING RESPIRATORY DISEASES | 2015 |
|
RU2577289C1 |
INHALATION FORMULATION IN FORM OF AEROSOL FOR TREATING BRONCHIAL ASTHMA AND CHRONIC OBSTRUCTIVE PULMONARY DISEASE | 2012 |
|
RU2504402C1 |
AEROSOL COMBINATION OF SALMETEROL AND FLUTICASONE FOR TREATING RESPIRATORY DISEASES | 2013 |
|
RU2521975C1 |
STABLE COMBINED SOLUTION OF FENOTEROL HYDROBROMIDE AND IPRATROPIUM BROMIDE | 2012 |
|
RU2493827C1 |
TROVENTOL-BASED COMPOSITION | 2006 |
|
RU2457832C2 |
PHARMACEUTICAL AEROSOL COMPOSITION | 2009 |
|
RU2565438C2 |
PHARMACEUTICAL COMPOSITION OF METERED AEROSOLS CONTAINING ANTIASTHMATIC AGENTS IN FORM OF SUSPENSIONS, SOLUTIONS, EMULSIONS, SOLUTIONS AND EMULSIONS | 2007 |
|
RU2356537C2 |
IPRATROPIUM BROMIDE SOLUTION | 2012 |
|
RU2496477C1 |
METHOD AND SYSTEM FOR MDI ELECTRONIC MODEL (DOSING INHALANT DEVICE) | 2012 |
|
RU2633269C2 |
Authors
Dates
2014-12-20—Published
2013-10-09—Filed