COMBINED AEROSOL PREPARATION FOR TREATING RESPIRATORY DISEASES Russian patent published in 2014 - IPC A61K31/46 A61K31/138 A61K9/08 A61K9/72 A61K47/10 A61K47/12 A61P11/06 A61P11/08 

Abstract RU 2536253 C1

FIELD: medicine.

SUBSTANCE: as active ingredients, a formulation contains fenoterol hydrobromide and ipratropium bromide monohydrate; the excipients are absolute ethanol, triethylcitrate, propellant 1,1,1,4 tetrafluoroethane (HFA-134a) and/or 1,1,1,2,3,3,3-heptafluoropropane (HFA-227ea) and a pharmaceutically acceptable acid specified in hydrochloric, orthophosphoric and citric acids.

EFFECT: increasing the respirable fraction and obtaining an optimised particle release profile.

2 dwg, 6 ex

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RU 2 536 253 C1

Authors

Malin Aleksandr Aleksandrovich

Mikhajlov Oleg Rostislavovich

Uvarov Nikolaj Aleksandrovich

Dates

2014-12-20Published

2013-10-09Filed