METHOD AND SYSTEM FOR MDI ELECTRONIC MODEL (DOSING INHALANT DEVICE) Russian patent published in 2017 - IPC A61M15/00 A61M16/20 

FIELD: medicine.

SUBSTANCE: method for aerosol cloud formation is performed by means of a device containing a metered-dose inhaler under pressure (MDI) containing the drug solution used with hydrofluoroalkane (HFA) propellants. The MDI inhaler volume is connected to an electronic valve. The valve is designed to receive control signals from the microprocessor. During method implementation, a set of drug parameters is stored in the memory device, this set comprises a quantitative indicator indicating the total amount of the aerosol medicament to be dispensed during the drug administration session; opening of the electronic valve is controlled, providing dosing of the total amount of the aerosolized drug during inhalation time by successive low-volume pulses. The time interval between pulses is between 20 and 50 ms. The volume of drug delivered during one pulse is less than 5 μl. Duration of each pulse is determined so that the fraction of respirable particles (FPF) of the aerosol drug is maximized and the amount of FPF fraction of the aerosol delivered during one pulse is calculated to minimize the inhalation time. An aerosol dispenser and a computer-readable medium for recording an aerosol cloud formation control program are disclosed.

EFFECT: ensured delivery of the optimal drug dose.

11 cl, 11 dwg, 8 tbl