NOVEL FUMARATE SALTS OF H3 HISTAMINE RECEPTOR ANTAGONISTS Russian patent published in 2015 - IPC C07D401/12 A61K31/4725 A61P3/10 A61P25/00 

Abstract RU 2537847 C2

FIELD: chemistry.

SUBSTANCE: invention relates to field of organic chemistry, namely to fumarate salts of 2-(cyclohexylmethyl)- N-{2-[(2S)-1-methylpyrrolidin-2yl]ethyl}-1,2,3,4-tetrahydroisoquinoline-7-sulphonamide, to based on them pharmaceutical compositions, method of their obtaining and methods of their application.

EFFECT: obtained are novel salts of 2-(cyclohexylmethyl)- N-{2-[(2S)-1-methylpyrrolidin-2yl]ethyl}-1,2,3,4-tetrahydroisoquinoline-7-sulphonamide, possessing properties of H3 histamine receptor antagonists.

16 cl, 9 dwg, 8 tbl, 6 ex

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RU 2 537 847 C2

Authors

Landzhevin Beverli S.

Farr Robert Allan

Shakh Dinubkhaj Kh.

Sherer Daniehl'

Dates

2015-01-10Published

2010-06-24Filed