POLYMORPHIC AND PSEUDOPOLYMORPHIC FORMS OF PHARMACEUTICAL COMPOUND Russian patent published in 2016 - IPC C07D471/08 A61K31/439 A61K31/4188 A61P31/04 

Abstract RU 2575173 C2

FIELD: chemistry.

SUBSTANCE: invention relates to organic chemistry, particularly to pseudopolymorphic forms 'A' and 'E', polymorphic forms 'B' and 'D' of a sodium salt of (1R,2S,5R)-7-oxo-6-sulphooxy-1,6-diazabicyclo[3.2.1]octane-2-carboxamide.

EFFECT: obtaining pseudopolymorphic and polymorphic forms of a sodium salt of (1R,2S,5R)-7-oxo-6-sulphooxy-1,6-diazabicyclo[3,2,1]octane-2-carboxamide, characterised by high stability in ambient conditions (at different temperatures and humidity), which can be used as a medicinal agent, particularly a β-lactamase inhibitor.

12 cl, 13 dwg, 12 ex

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RU 2 575 173 C2

Authors

Bhattachrya Sisir

Bonnet Alain

Dedhiya Mahendra G.

Ducandas Veronigue

Giuliani Alexandre

Priour Alain

Ravaux Valerie

Spargo Peter

Dates

2016-02-20Published

2010-10-08Filed