FIELD: chemistry.
SUBSTANCE: invention relates to method of obtaining 4,5-dicyanophthalic acid, which can be applied as initial compound in synthesis of 2,3,9,10,16,17,23,24-octacarboxyphthalocyanines, used in therapy of oncologic diseases. In accordance with the claimed method the first stage includes interaction of 4,5-dicarboxyphthalimide with water ammonia solution with opening of imide cycle and obtaining ammonium salt of 4,5-dicarboxyphthalamide. The second stage includes dehydration of obtained salt by interaction with dehydrating agents in molar ratio 1:3 in dimethylformamide at 5-0°C with further exposure at room temperature with obtaining 4,5-dicyanophthalic acid. Phosphorus oxychloride or thionyl chloride is preferably used as dehydrating agent.
EFFECT: method makes it possible to obtain target product with good output.
2 cl, 7 ex
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