FIELD: chemistry.
SUBSTANCE: invention relates to synthesis of imidoyl chlorides, which are intermediates in synthesis of biologically active chemical compounds, more specifically to a method of producing imidoyl chloride derivatives of general formula given below, where R=-H, -CH3, -OCH3, -C4H9, Br. Method comprises reacting a derivative of N-aryl-1-adamantane carboxamide with a chlorinating agent at 75-80 °C for 1 hour with further extraction of reaction product. Method is characterised by that reaction is carried out in presence of a 4-(N,N-dimethylamino)pyridine catalyst, and chlorinating agent used is phosphorus trichloride with molar ratio N-aryl-1-adamantane carboxamide, phosphorus trichloride and 4-(N,N-dimethylamino)pyridine equal to 1:5:1.
EFFECT: disclosed method enables to obtain said imidoyl chloride derivatives with high output.
1 cl, 5 ex
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