FIELD: medicine.
SUBSTANCE: group of inventions refers to medicine and can be used for treating an individual having a slowly healing or chronic wound. That is ensured by administering a composition containing therapeutically effective amounts of an anti-connexin43 agent, and a protein or a peptide effective for stimulating or improving the wound healing into the individual in need thereof. What is also presented is using the therapeutically effective amount of a first wound-healing compound and a second wound-healing compound, wherein the above first wound-healing compound represents the anti-connexin43 agent, while the above second wound-healing compound is specified in a group consisting of beta-adrenergic antagonists, interleukin-1 receptor antagonists, free radical scavengers, anti-inflammatory and antimicrobial agents, opioids, connexin phosphorylation agents.
EFFECT: group of inventions provides higher rate and/or quality of wound healing by means of using the above combination of the therapeutic agents when it is possible to reduce the dose and rate of administration.
46 cl, 19 dwg, 8 tbl, 11 ex
Authors
Dates
2015-02-20—Published
2007-11-15—Filed