METHOD FOR BIOENCAPSULATION Russian patent published in 2015 - IPC A61K31/545 A61K9/50 A61K47/34 A61J3/07 B01J13/02 

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention refers to bioencapsulation, namely to a method for cephalosporin bioencapsulation, wherein poludan is used as a microcapsule coating. The declared method is characterised by adding a cephalosporin powder 0.060 g and the E472 preparation 0.05 g as a surfactant to 1% aqueous poludan 2 g. The prepared mixture is mixed; after the reaction mixture ingredients are dissolved to prepare a transparent solution, carbinol 1 ml as the first precipitation agent, and acetone 5 ml as the second precipitation agent are added drop by drop very slowly. The prepared microcapsule suspension is filtered in a filter, washed in acetone and dried in a drying cabinet; the method is implemented at 25°C.

EFFECT: simplifying and fastening the process of microencapsulation in poludan and higher weight yield.

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