FIELD: medicine, pharmaceutics.
SUBSTANCE: invention relates to the chemical-pharmaceutical industry and represents a method of encapsulating cephalosporin group medications, characterised by the application of albumin as an envelope for microcapsules, with 0.450 g of cephalosporin antibiotic powder and 0.02 g of E472c preparation being added to 6 g of a 2.5% water albumin solution at 25°C with further mixing until a transparent solution is formed, after that 5 ml of isopropanol, and then 15 ml of acetone are added slowly, drop-by-drop, the obtained suspension of the microcapsules is filtered, washed with acetone and dried.
EFFECT: invention provides the simplification and acceleration of the process of obtaining microcapsules, reduction of loss in obtaining the microcapsules (increase of output by weight).
3 ex
Title | Year | Author | Number |
---|---|---|---|
METHOD FOR CEPHALOSPORIN BIOENCAPSULATION | 2013 |
|
RU2538806C2 |
METHOD FOR CEPHALOSPORIN BIOENCAPSULATION | 2013 |
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RU2539898C2 |
METHOD OF BIOENCAPSULATION OF CEPHALOSPORIN GROUP MEDICATIONS | 2013 |
|
RU2554277C2 |
METHOD FOR CEPHALOSPORIN BIOENCAPSULATION | 2013 |
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RU2542417C2 |
METHOD OF BIOENCAPSULATION | 2013 |
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RU2558077C2 |
METHOD FOR CEPHALOSPORIN BIOENCAPSULATION | 2013 |
|
RU2537251C1 |
METHOD FOR BIOENCAPSULATION | 2013 |
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RU2538646C1 |
METHOD FOR BIOENCAPSULATION | 2013 |
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RU2538678C2 |
METHOD FOR BIOENCAPSULATION | 2013 |
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RU2538807C1 |
METHOD OF BIOENCAPSULATION | 2013 |
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RU2538668C1 |
Authors
Dates
2015-04-10—Published
2013-05-29—Filed