METHOD OF BIOENCAPSULATION OF CEPHALOSPORIN GROUP MEDICATIONS Russian patent published in 2015 - IPC A61K9/50 A61K31/545 B01J13/06 

Abstract RU 2545723 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention relates to the chemical-pharmaceutical industry and represents a method of encapsulating cephalosporin group medications, characterised by the application of albumin as an envelope for microcapsules, with 0.450 g of cephalosporin antibiotic powder and 0.02 g of E472c preparation being added to 6 g of a 2.5% water albumin solution at 25°C with further mixing until a transparent solution is formed, after that 5 ml of isopropanol, and then 15 ml of acetone are added slowly, drop-by-drop, the obtained suspension of the microcapsules is filtered, washed with acetone and dried.

EFFECT: invention provides the simplification and acceleration of the process of obtaining microcapsules, reduction of loss in obtaining the microcapsules (increase of output by weight).

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RU 2 545 723 C2

Authors

Bykovskaja Ekaterina Evgen'Evna

Krolevets Aleksandr Aleksandrovich

Dates

2015-04-10Published

2013-05-29Filed