METHOD OF MICROCAPSULATION OF CEPHALOSPORIN ANTIBIOTICS IN POLUDANUM Russian patent published in 2015 - IPC A61K9/50 A61K31/545 A61K47/30 A61J3/07 

FIELD: medicine.

SUBSTANCE: invention relates to field of microcapsulation, in particular to method of obtaining microcapsules of medications of cephalosporin group. Method is characterised by the fact that as envelope of microcapsules applied is poludanum, powder of medication of cephalosporin group is added to poludanum water solution in presence of surface-active substance E 472c, ratio of poludanum amount and medication of cephalosporin group in counted per dry substance constitutes 3:1, obtained mixture is mixed to complete dissolution of reaction mixture components and carbinol is added drop-by-drop as first precipitator, and then diethyl ether is added as second precipitator, obtained suspension of microcapsules is filtered, washed by acetone, and dried in exsiccator.

EFFECT: method ensures simplification and acceleration of process of obtaining microcapsules of water-soluble medications of cephalosporin group in poludanum, reduction of loss in the process of obtaining microcapsules.

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