METHOD OF TREATING ONCOLOGICAL DISEASES Russian patent published in 2015 - IPC A61M31/00 A61K47/00 B82B1/00 

Abstract RU 2546299 C2

FIELD: medicine.

SUBSTANCE: invention refers to medicine and veterinary science, namely to a targeted drug delivery into a living body. The object of the presented invention is simplifying the process of the targeted drug delivery into the malignant new growth and increasing the local drug delivery into the tumour. The assigned object is achieved by administering drugs from the group of antitumour chemotherapeutic preparations fixed on a solid carrier into a patient's body by placing one or more drug containers immediately into the tumour tissue in blocks with a block volume related to its outer surface as 10-1500 mcm, consisting of a biocompatible porous base having a porosity of 40-75 vol. % pores of which comprise the drug in an amount of 1-100 mg in 1 cm3 of the porous base, while the number of the drug containers placed into the tumour is specified from the relation Vtum=(2-2000)·n·Vdc, wherein Vtum is the tumour volume, n is the number of the placed drug containers, Vdc is the drug container volume.

EFFECT: presented method provides the targeted drug delivery into the tumour tissues, thereby providing the tumour cell death that is necessary in treating tumour diseases; the method is simple and requires no complicated technical devices to be used.

5 cl, 2 ex

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RU 2 546 299 C2

Authors

Gordeev Sergej Konstantinovich

Kuril'Chik Aleksandr Aleksandrovich

Konopljannikov Anatolij Georgievich

Korchagina Svetlana Borisovna

Filimonova Marina Vladimirovna

Juzhakov Vadim Vasil'Evich

Tsyb Anatolij Fedorovich

Kiselev Oleg Ivanovich

Dates

2015-04-10Published

2013-07-03Filed