FIELD: medicine.
SUBSTANCE: first stage of the treatment in the patients with a primary inoperable form of uterine cancer involves a neoadjuvant polychemotherapy combined with a session of therapeutic plasmapheresis. The chemotherapy is preceded with a session of discrete gravity plasmapheresis by means of MCS apparatus + PPP (platelet-poor plasma) Hemonetics. The chemotherapeutic agents are administered on the day following the plasmapheresis session.
EFFECT: method enables overcoming the tumour resistance to cytostatics, reducing the number of the pre-operative chemotherapeutic courses, downsizing the tumour and improving the tumour process respectability, reducing toxic and side chemotherapeutic responses, and reducing cytostatic doses.
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