FIELD: medicine.
SUBSTANCE: invention relates to medicine, namely to oncogynecology, and can be used to predict the progression of cervical cancer in stage IIB patients. After neoadjuvant chemotherapy, the level of CD44 expression is determined intraoperatively in the tumor tissue by immunohistochemical method. At its level above 25%, the development of disease progression is predicted within 10-27 months.
EFFECT: method makes it possible to predict the progression of cervical cancer in stage IIB patients after complex treatment, including neoadjuvant chemotherapy, by determining the level of expression in the tumor tissue of the tumor stem cell marker CD44, which is an adhesion molecule.
1 cl, 2 tbl, 2 ex
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Authors
Dates
2023-02-03—Published
2022-07-05—Filed