METHOD FOR PREDICTING THE PROGRESSION OF CERVICAL CANCER IN PATIENTS WITH STAGE IIB Russian patent published in 2023 - IPC G01N33/574 

Abstract RU 2789500 C1

FIELD: medicine.

SUBSTANCE: invention relates to medicine, namely to oncogynecology, and can be used to predict the progression of cervical cancer in stage IIB patients. After neoadjuvant chemotherapy, the level of CD44 expression is determined intraoperatively in the tumor tissue by immunohistochemical method. At its level above 25%, the development of disease progression is predicted within 10-27 months.

EFFECT: method makes it possible to predict the progression of cervical cancer in stage IIB patients after complex treatment, including neoadjuvant chemotherapy, by determining the level of expression in the tumor tissue of the tumor stem cell marker CD44, which is an adhesion molecule.

1 cl, 2 tbl, 2 ex

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RU 2 789 500 C1

Authors

Zlatnik Elena Iurevna

Menshenina Anna Petrovna

Ulianova Elena Petrovna

Moiseenko Tatiana Ivanovna

Frantsiiants Elena Mikhailovna

Verenikina Ekaterina Vladimirovna

Polovodova Veronika Vasilevna

Dates

2023-02-03Published

2022-07-05Filed