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2 613 888

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IPC

A61K31/282(2006-01-01)

A61P35/00(2006-01-01)

(21) (22)

Application

2016106990, 2016-02-26

(24)

Start date

2016-02-26

(22)

Actual filing date

2016-02-26

(45)

Published

2017-03-21

(72)

Inventor

Chernobrovkina Alla EvgenevnaBalakhnin Pavel VasilevichMaksimov Sergej YanovichBazhenov Artem GrigorevichIlin Anton AlekseevichShmelev Aleksej Stanislavovich

(73)

Holder

Gosudarstvennoe Byudzhetnoe Uchrezhdenie Zdravookhraneniya Klinicheskij Nauchno-Prakticheskij Tsentr Spetsializirovannykh Vidov Meditsinskoj Pomoshchi

METHOD FOR PREOPERATIVE TREATMENT OF PATIENTS WITH LOCALLY ADVANCED CERVICAL CANCER AT T1b2-T2b STAGE Russian patent published in 2017 - IPC A61K31/282 A61P35/00

Abstract RU 2613888 C1

FIELD: medicine.

SUBSTANCE: invention can be used to pre-treat T1b2-T2b locally advanced cervical cancer (CC). The method comprises superselective chemoembolization of cervical arteries. Then the ascending branches of uterine arteries are cut off from the blood flow by their redistributive embolization using a hemostatic sponge. Then uterine artery chemoembolization is performed, when the superselective chemoembolization of cervical arterial and chemoembolization of uterine arteries uses 25 mg of drug-saturable HepaSpheres microspheres with dry particle size of 50-100 microns, which is saturated with 100 mg of oxaliplatin diluted in a non-ionic contrast agent.

EFFECT: use of the invention can improve the efficiency of drug-saturable microspheres delivery to the cervical tumor, which reduces the risk of damage to adjacent organs and tissues and prevents the development of ischemia and necrosis.

4 dwg, 2 ex

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RU 2 613 888 C1

Authors

Chernobrovkina Alla Evgenevna

Balakhnin Pavel Vasilevich

Maksimov Sergej Yanovich

Bazhenov Artem Grigorevich

Ilin Anton Alekseevich

Shmelev Aleksej Stanislavovich

Dates

2017-03-21—Published

2016-02-26—Filed