FIELD: medicine.
SUBSTANCE: invention provides a solid hypolipidemic dosage form containing rosuvastatin or its pharmaceutically acceptable salt in an amount of 3 to 15%, processing additives and a pharmaceutically acceptable excipient containing microcrystalline cellulose, lactose monohydrate, polyvinylpyrrolidone and croscarmellose sodium. The above excipient represents granulate in an amount of 79 to 95 wt % of the dosage form containing absorbed moisture within the range of 0.5% to 1.5%. What is also described is a method for preparing the dosage form.
EFFECT: uniform distribution of the active substance and storage stability of the dosage form of rosuvastatin.
11 cl, 3 tbl
Authors
Dates
2015-04-10—Published
2013-07-09—Filed