SOLID DOSAGE FORM HAVING HYPOLIPIDEMIC AND HYPOCHOLESTEREMIC ACTIVITY, AND METHOD OF ITS PRODUCTION Russian patent published in 2010 - IPC A61K31/40 A61K47/38 A61K47/26 A61K9/30 A61J3/10 A61P3/06

Abstract RU 2404767 C1

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention relates to pharmaceutical industry and solid dosage form of calcium atorvastatin. Solid dosage form consists of core containing the following components, wt %: calcium atorvastatin - 1.5-25; microcrystalline cellulose - 2-30; calcium carbonate - 5-30; croscarmellose sodium - 0.5-5; stearic acid and/or its salt - 0.5-1.04; lactose "Lactopress Spraydry" - balance; and shell containing the following components, wt %: polyethylene glycol - 6-28; titanium dioxide - 10-35; talc - 5-25; silicon emulsion - 0.05-4; dye - 0-3; polyvinyl alcohol - balance.

EFFECT: invention provides for production of calcium atorvastatin pills satisfying requirements of National pharmacopeia XI.

4 cl, 5 tbl

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Authors

Dates

2010-11-27—Published

2009-08-11—Filed