METHOD FOR SIMULATING ACUTE DESTRUCTIVE INFECTED PANCREONECROSIS Russian patent published in 2015 - IPC G09B23/28 

FIELD: medicine.

SUBSTANCE: method involves laparotomy in Wistar rats with inserting a complex of spleen and pancreas into the wound. That is followed by cryodestruction of a portion of pancreas for 5 sec with the use of an applicator of the area of 0.6 cm² cooled in liquid nitrogen for 40 sec. That is followed by immersing the complex of the pancreas and spleen into the limited cavity pre-formed of the abdominal external and internal oblique muscles. That is followed by introducing S.aureus microbial suspension 0.3 ml 1 billion into this cavity. Before closing the incisional wound, a fistula is attached to leaves of the external oblique muscles for the following administration of drug preparations into the formed cavity.

EFFECT: providing the controlled simulation of pancreonecrosis close to that developing in the clinical settings.

6 dwg, 4 tbl, 1 ex