FIELD: medicine, pharmaceutics.
SUBSTANCE: invention relates to field of encapsulation, in particular to method of obtaining microcapsules Biopag-D in envelope of human leukocytic interferon (β- or α-interferon). According to invention method, suspension of Biopag-D in water is added to 1-% water solution of interferon in presence of medication E472c and mixed to transparent solution. Suspension of Biopag-D and interferon solution are taken in weight ratio 3:1 or 2.5:1. Butanol, and then acetone taken in ratio 1:5% vol/vol are added. Obtained suspension of microcapsules is filtered, washed and dried. Process of obtaining microcapsules is realised at 25°C for 15 min.
EFFECT: invention ensures simplification and acceleration of process of obtaining microcapsules, reduction of loss in the process of their obtaining (increase of output by weight).
3 ex
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Authors
Dates
2015-05-10—Published
2013-08-01—Filed