FIELD: medicine.
SUBSTANCE: invention relates to medicine and consists in method of producing microcapsules of cephalosporin preparations, in which envelope is interferon, core is preparations of cephalosporins. During method implementation cephalosporin preparations and E472c as surfactant are added to aqueous solution of interferon, obtained mixture is mixed in magnetic stirrer until dissolving of mixture components to produce transparent solution, then slowly chloroform is added by drops, obtained suspension is filtered, washed with chloroform and dried, wherein ratio shell:core is 3:1.
EFFECT: technical result consists in simplifying and accelerating of production of nanocapsules, as well as increase of mass output.
1 cl, 1 dwg, 9 ex
Title | Year | Author | Number |
---|---|---|---|
METHOD OF PRODUCING ANTIBIOTIC NANOCAPSULES IN INTERFERON | 2014 |
|
RU2584226C2 |
METHOD OF BIOENCAPSULATION | 2013 |
|
RU2558077C2 |
METHOD OF BIOENCAPSULATION | 2013 |
|
RU2555466C2 |
METHOD FOR BIOENCAPSULATION | 2013 |
|
RU2538678C2 |
METHOD OF BIOENCAPSULATION | 2013 |
|
RU2538668C1 |
METHOD OF PRODUCING MICROCAPSULES OF CEPHALOSPORIN ANTIBIOTICS IN INTERFERONS | 2013 |
|
RU2580614C2 |
METHOD OF BIOENCAPSULATION | 2013 |
|
RU2549959C2 |
METHOD FOR BIOENCAPSULATION | 2013 |
|
RU2538807C1 |
METHOD FOR BIOENCAPSULATION | 2013 |
|
RU2538646C1 |
METHOD FOR PREPARING CEPHALOSPORIN MICROCAPSULES IN INTERFERON | 2012 |
|
RU2500404C2 |
Authors
Dates
2016-12-27—Published
2014-10-10—Filed