METHOD FOR PREVENTING AND TREATING ACUTE RADIATION DISEASE EXPERIMENTALLY Russian patent published in 2015 - IPC G09B23/28 A61K38/02 A61P17/18 A61P39/06 

Abstract RU 2551619 C1

FIELD: medicine.

SUBSTANCE: melanin having water-solubility of at least 80% and an paramagnetic centre concentration of at least 8·1017 spin/g is administered orally into the animals having been exposed to the radiation in a dose high enough to cause a spinal radiation injury; melanin is administered after dissolved in distilled water in the effective concentration. Melanin water is used as drinking water for the mice having been exposed to single and fractionated acute radiation, which is able to cause acute radiation disease. Melanin water is taken from the 1st to 30th day following the single radiation, or from the 1st day of the fractionated radiation to the 30th day on completion of the radiation.

EFFECT: higher survival rate, faster recovered haemopoiesis, body weight and orientation and motion activity.

7 tbl, 5 ex

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RU 2 551 619 C1

Authors

Kotenko Konstantin Valentinovich

Bushmanov Andrej Jur'Evich

Ivanov Aleksandr Aleksandrovich

Abrosimova Alla Nikolaevna

Andrianova Irina Efimovna

Bulynina Taisija Mikhajlovna

Vorozhtsova Svetlana Vladimirovna

Dorozhkina Ol'Ga Vasil'Evna

Severjukhin Jurij Sergeevich

Stavrakova Nina Mikhajlovna

Dates

2015-05-27Published

2014-05-19Filed