METHOD FOR MODELLING ACUTE RADIATION SICKNESS IN EXPERIMENT Russian patent published in 2024 - IPC A61N5/10 G09B23/28 

Abstract RU 2811270 C1

FIELD: experimental medicine.

SUBSTANCE: invention can be used to simulate acute radiation sickness (ARS) in experiments. Experimental animals are placed in individual containers. Containers with experimental animals are placed between plates of a solid-state water-equivalent phantom measuring 30x30 cm2, height 1 cm and density 1.032 g/cm3. The volume of irradiation is modelled based on the size of containers, which are assigned a density of 1 g/cm3, and plates of a solid-state water-equivalent phantom. After this, experimental animals are irradiated once using the Elekta Precise accelerator in doses of 8 to 9 Gy at a dose rate of 4.2 Gy/min.

EFFECT: method provides modelling of development of the clinical symptoms of ARS and allows reproducing the results obtained during irradiation through the use of plates of a solid-state water-equivalent phantom.

1 cl, 1 dwg, 2 ex

Similar patents RU2811270C1

Title Year Author Number
RADIATION CYSTITIS MODELING METHOD 2018
  • Korytov Oleg Vitalevich
  • Korytova Luiza Ibragimovna
  • Ponezha Tamara Evgenevna
  • Maslyukova Elizaveta Aleksandrovna
  • Bondarenko Anna Vladimirovna
  • Sokurenko Valentina Petrovna
  • Akhtemzyanov Artur Ramilevich
  • Bespalov Vladimir Grigorevich
  • Bryntsalova Anna Aleksandrovna
  • Semenov Aleksandr Leonidovich
  • Ivanov Sergej Dmitrievich
  • Zhabina Razifa Midkhatovna
RU2676431C1
METHOD FOR SIMULATING COMBINED RADIATION INJURIES INVOLVING GENERAL GAMMA- AND LOCAL X-RAY EXPOSURE 2013
  • Grebenjuk Aleksandr Nikolaevich
  • Legeza Vladimir Ivanovich
  • Zargarova Nina Ivanovna
  • Vladimirova Ol'Ga Olegovna
RU2527148C1
METHOD FOR PREVENTING AND TREATING ACUTE RADIATION DISEASE EXPERIMENTALLY 2014
  • Kotenko Konstantin Valentinovich
  • Bushmanov Andrej Jur'Evich
  • Ivanov Aleksandr Aleksandrovich
  • Abrosimova Alla Nikolaevna
  • Andrianova Irina Efimovna
  • Bulynina Taisija Mikhajlovna
  • Vorozhtsova Svetlana Vladimirovna
  • Dorozhkina Ol'Ga Vasil'Evna
  • Severjukhin Jurij Sergeevich
  • Stavrakova Nina Mikhajlovna
RU2551619C1
LIPOSOME, PHARMACEUTICAL COMPOSITION AND DRUG FOR TREATMENT OF LOCAL RADIATION SKIN LESIONS, LIPOSOME APPLICATION AND METHOD FOR LOCAL RADIATION SKIN LESIONS TREATMENT 2016
  • Akleev Aleksandr Vasilevich
  • Dudich Igor Vyacheslavovich
  • Ostroumov Yurij Igorevich
  • Semenkova Lidiya Nikolaevna
  • Benevolenskij Sergej Vladimirovich
  • Tryapitsyna Galina Aleksandrovna
  • Atamanyuk Natalya Igorevna
  • Obvintseva Nadezhda Aleksandrovna
  • Pryakhin Evgenij Aleksandrovich
RU2642957C2
METHOD FOR SIMULATING COMBINED RADIATION INJURIES INVOLVING WHOLE-BODY GAMMA- AND LOCAL BETA-RADIATION 2013
  • Grebenjuk Aleksandr Nikolaevich
  • Legeza Vladimir Ivanovich
  • Zargarova Nina Ivanovna
  • Vladimirova Ol'Ga Olegovna
RU2534802C1
METHOD FOR TOTAL IRRADIATION OF THE BODY OF A PATIENT 2021
  • Ponezha Tamara Evgenevna
  • Vinogradova Iuliia Nikolaevna
  • Ilin Nikolai Vasilevich
  • Shenderova Irina Aleksandrovna
  • Karpenko Elena Draganovna
RU2760613C1
METHOD FOR SIMULATING RADIATION PULMONITIS IN EXPERIMENT 2023
  • Korytov Oleg Vitalevich
  • Korytova Luiza Ibragimovna
  • Makarov Viktor Evgenevich
  • Ponezha Tamara Evgenevna
  • Kartashev Artem Vladimirovich
  • Popova Alena Aleksandrovna
  • Bryntsalova Anna Aleksandrovna
  • Morozova Anna Valerevna
RU2816074C1
AGENT FOR EARLY TREATMENT OF PATIENTS WITH RADIATION AND COMBINED RADIATION-THERMIC DAMAGES 1995
  • Pospelova V.V.
  • Rakhimova N.G.
  • Khanina G.I.
  • Ul'Janova L.P.
  • Budagov R.S.
  • Makarov G.F.
RU2123344C1
METHOD FOR MODELING CHRONIC ISCHEMIA IN EXPERIMENTAL ANIMALS. 2022
  • Korytov Oleg Vitalevich
  • Korytova Luiza Ibragimovna
  • Morozova Anna Valerevna
  • Makarov Viktor Evgenevich
  • Popova Alena Aleksandrovna
  • Maistrenko Dmitrii Nikolaevich
RU2777184C1
METHOD OF MODELING ACUTE POST-RADIATION PNEUMONITIS IN LABORATORY ANIMALS 2023
  • Pashkovskaia Oksana Aleksandrovna
  • Sergeevichev David Sergeevich
  • Krasilnikov Sergei Eduardovich
  • Murashov Ivan Sergeevich
RU2810437C1

RU 2 811 270 C1

Authors

Maistrenko Dmitrii Nikolaevich

Molchanov Oleg Evgenevich

Popova Alena Aleksandrovna

Nikolaev Dmitrii Nikolaevich

Vinogradova Iuliia Nikolaevna

Ponezha Tamara Evgenevna

Semenov Konstantin Nikolaevich

Sharoiko Vladimir Vladimirovich

Protas Aleksandra Vladimirovna

Mikolaichuk Olga Vladislavovna

Evtushenko Vladimir Ivanovich

Popova Elena Aleksandrovna

Dates

2024-01-11Published

2023-06-19Filed