FIELD: chemistry.
SUBSTANCE: invention refers to a method for the one-stage production of (3-hydroxypropyl)naphthols of having a structure of R1=CH2CH2CH2OH, R2=OH, R3=H; R1=OH, R2=CH2CH2CH2OH, R3=H; R1=OH, R2=CH2CH2CH2OH, R3=CH2CH2CH2OH; R1=OH, R2=T-Bu, R3=CH2CH2CH2OH, effective biologically active substances of neutropic action. The method consists in conducting a reaction of α-, β-naphthols, their derivatives or their sodium salts with allyl alcohol and alkali at temperature 100-170°C. A purified product yield is 40-60%.
EFFECT: higher yield.
4 ex
Authors
Dates
2015-05-27—Published
2014-05-15—Filed