FIELD: medicine.
SUBSTANCE: clinical anamnestic parameters are determined in the patients with hyperplastic processes in the endometrium, and a hysteroscopy with an endometrial biopsy is performed. The activity of calpains, total activity of proteasomes, and activity of 20S proteasomes are determined. Age-dependent discriminator functions Y1 and Y2 are determined by formulas. If Y1>Y2, the patient is referred to a group of low risk of endometrial cancer development. If Y1<Y2, the patient is referred to a group of high risk of endometrial cancer development.
EFFECT: invention enables the high-sensitivity and specificity prediction of endometrial cancer development in the patients suffering from the hyperplastic processes in the endometrium.
1 tbl, 3 ex
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