MONOCLONAL ANTIBODIES CAPABLE OF BINDING WITH AXL PROTEIN AND THEIR APPLICATION Russian patent published in 2015 - IPC C07K16/32 C12N5/12 A61K39/395 A61P35/00 

Abstract RU 2559530 C2

FIELD: medicine.

SUBSTANCE: claimed invention relates to field of biotechnology. Claimed antibodies which bind with fibronectin type-III domain 1 (FND1) of AXL protein and cause AXL deactivation, as well as application of said antibodies for suppression of growth of malignant tumour, mediated by AXL, hybridomas, producing them and composition for suppression of growth of AXL-mediated malignant tumour, which contains antibody in accordance with claimed invention as active ingredient.

EFFECT: obtaining antibodies for suppression of malignant tumour growth.

12 cl, 7 dwg, 2 tbl, 12 ex

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RU 2 559 530 C2

Authors

Kitazava, Takekhisa

Suzuki, Tsukasa

Nagakhasi, Sigekhisa

Mijamoto, Khadzime

Dates

2015-08-10Published

2008-11-14Filed