FIELD: medicine.
SUBSTANCE: claimed invention relates to field of biotechnology. Claimed antibodies which bind with fibronectin type-III domain 1 (FND1) of AXL protein and cause AXL deactivation, as well as application of said antibodies for suppression of growth of malignant tumour, mediated by AXL, hybridomas, producing them and composition for suppression of growth of AXL-mediated malignant tumour, which contains antibody in accordance with claimed invention as active ingredient.
EFFECT: obtaining antibodies for suppression of malignant tumour growth.
12 cl, 7 dwg, 2 tbl, 12 ex
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Authors
Dates
2015-08-10—Published
2008-11-14—Filed