FIELD: biochemistry.
SUBSTANCE: invention relates to biochemistry, particularly to an antibody which specifically binds to CAPRIN-1 protein. Invention also discloses a monoclonal antibody having immunological reactivity to CAPRIN-1 protein, antibodies which specifically bind with CAPRIN-1 protein, a medicinal agent containing said antibodies for treating or preventing CAPRIN-1 expressing cancer. Disclosed are methods of treating or preventing CAPRIN-1 expressing cancer, using disclosed antibody and said medicinal agent.
EFFECT: invention is capable of specifically binding to CAPRIN-1, which provides effective treatment of diseases associated with expression of CAPRIN-1 protein.
16 cl, 2 dwg, 7 ex
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