FIELD: medicine, pharmaceutics.
SUBSTANCE: invention relates to the pharmaceutical industry, namely to a system for delivering biologically active substances into an organism. The system for delivering biologically active substances into the organism represents a nanodiamond with the particle size of 2-10 nm, the surface of which is modified with chlorine with the chlorine content up to 14 atomic%. A method of obtaining the system for delivering biologically active substances into the organism, representing the nanodiamond with the particle size of 2-10 nm, the surface of which is modified with chlorine with the chlorine content to 14 atomic% consists in the fact that annealing of the nanodiamond particles is carried out at a temperature of 500-1200°C in the flow of gaseous hydrogen with the further liquid-phase chlorination of the obtained particles with molecular chlorine, dissolved in carbon tetrachloride under a photochemical impact of visible light and heating, after which the suspension is centrifuged, washed and dried under specified conditions.
EFFECT: said method makes it possible to obtain the system for delivering biologically active substances into the organism, representing nanodiamond particles, which do not contain fluorine, capable of effective binding of various biologically active and medicinal substances.
8 cl, 13 dwg, 3 tbl, 11 ex
Title | Year | Author | Number |
---|---|---|---|
NANODIAMOND- GLYCINE CONJUGATE AND METHOD OF OBTAINING THEREOF | 2011 |
|
RU2560700C2 |
ANTIBACTERIAL AGENT AND METHOD FOR PREPARING IT | 2012 |
|
RU2476215C1 |
CONJUGATE OF NANODIAMOND WITH PYROPHOSPHATASE AND METHOD OF OBTAINING THEREOF | 2013 |
|
RU2542411C1 |
ANTIOXIDANT AND METHOD FOR PREPARING IT | 2013 |
|
RU2519760C1 |
METHOD FOR QUANTITATIVE MEASUREMENT OF CARBON NANOSTRUCTURES IN BIOLOGICAL SAMPLES AND BODY DISTRIBUTION THEREOF | 2013 |
|
RU2528096C1 |
METHOD FOR QUANTITATIVE ESTIMATION OF CHEMICALLY COMBINED ORGANIC SUBSTANCE WITH NANODIAMOND | 2011 |
|
RU2555350C2 |
ANTIHYPOXANT AND METHOD FOR PREPARING IT | 2013 |
|
RU2506074C1 |
ANXIOLYTIC AND METHOD FOR PREPARING IT | 2013 |
|
RU2519755C1 |
ANTIDEPRESSANT DRUG AND METHOD FOR PREPARING IT | 2013 |
|
RU2519759C1 |
ANTICONVULSANT AND METHOD FOR PREPARING IT | 2013 |
|
RU2508098C1 |
Authors
Dates
2015-08-20—Published
2011-07-26—Filed