FIELD: chemistry.
SUBSTANCE: claimed invention relates to method of alginate ultrapurification. Method of obtaining solutions of alginate salts includes addition of technical alginate powder to salt solution in order to obtain alginate solution with concentration from 1.6 to 2.0 wt % and bringing pH to 7.4-7.6, filtration of obtained alginate solution on at least one hydrophilic filter and extraction of filtered alginate solution. After that, filtered alginate solution is filtered on charge-modified hydrophobic nylon filter, with further extraction of alginate solution. Final alginate solution, which has not been subjected to structural modification, with content of endotoxins lower than 20 EU/g is obtained.
EFFECT: invention makes it possible to obtain alginate solution with high degree of purification from endotoxins and eliminate dialysis stage in purification.
12 cl, 1 tbl, 2 ex
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Authors
Dates
2015-08-20—Published
2009-01-21—Filed