USE OF ALGINATE SALT AS LIPID SORBENT, PHARMACEUTICAL COMPOSITION AND MEDICAMENT FOR TREATMENT OF OBESITY Russian patent published in 2018 - IPC A61K31/734 A61K9/16 A61P39/00 A61P3/06 B01J20/24 B01J20/285 

FIELD: pharmaceutics.

SUBSTANCE: group of inventions refers to pharmaceuticals, namely to drug that can be used in medicine. It is proposed: use of granules of a salt of a two- or trivalent metal of alginate 0.1–2 mm in size as a lipid sorbent, inhibiting their cleavage; pharmaceutical composition for reducing the absorption of lipids in the gastrointestinal tract, containing said granules in an effective amount and pharmaceutically acceptable excipients and medicament for treating obesity, which is a solid oral dosage form with a pharmaceutical composition. Technical result: calcium alginate granules are capable of sorbing lipids from the food lump and preventing their fermentation, thus preventing absorption in digestive tract and reducing total caloric value; the formation of free fatty acids from olive oil was inhibited by 23 % with alginate granules compared to alginate without granules. Drug can be successfully used to treat obesity and has no side effects of analogues. Invention also allows to expand the range of drugs used to treat obesity.

EFFECT: technical result: calcium alginate granules are capable of sorbing lipids from food lump and preventing their fermentation.

11 cl, 5 dwg, 4 tbl