FIELD: medicine.
SUBSTANCE: correcting neurological disturbances accompanying alcohol intoxication in rats is ensured by prescribing a metabolitotropic agent containing both the active substance (S)-2,6-diaminohexanoic acid 3-methyl-1,2,4-triazolyl-5-thioacetate (Angioline), also having a neuroprotective and endothelioprotective action, in a dose of 100 mg/kg a day for 14 days.
EFFECT: high therapeutic effectiveness of Angiolin in alcohol intoxication, an ability to correct neurological disturbances effectively, reducing manifested hyperactivity and aggression, normalising the central nervous system functions as compared to the reference preparation mildronat.
4 tbl
Title | Year | Author | Number |
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3-METHYL-1,2,4-TRIAZOLE-5-THIOACETATE (S) -2,6-DIAMINOHEXANE ACID APPLICATION AS ACTIVE DRUG BASE FOR PREVENTION AND TREATMENT OF CNS VITAL FUNCTIONS IN CASE OF SEVERE FORMS OF ACUTE ETHANOL POISONING | 2016 |
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Authors
Dates
2015-08-20—Published
2014-07-01—Filed