METHOD FOR PRODUCING THYROID HORMONES AND SALTS THEREOF Russian patent published in 2015 - IPC C07C227/16 C07C229/36 

Abstract RU 2561125 C2

FIELD: medicine.

SUBSTANCE: invention refers to a method for producing thyroid hormones of formula

The method involves carrying out a reaction of a compound of formula with an iodinating agent containing NaI and I2 in the presence of aliphatic amine to produce a disodium derivative of formula II as a raw material. The produced alcohol water alkaline solution of the compound of formula II having pH at least 11 is heated to a temperature of 40°C to 80°C, cooled down to a temperature of 5°C to 20°C, and the compound II is recovered as a pure solid material.

EFFECT: presented method enables the one-stage production of high-yield and high-purity disodium salt II.

14 cl, 1 tbl, 3 ex

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RU 2 561 125 C2

Authors

Viskardi Karlo Feliche

Gatstsetto Sonja

Galimberti Laura

Kappelletti Ehnriko

Sini Loredana

Dates

2015-08-20Published

2010-12-17Filed