METHOD OF PRODUCING SULPHATED DERIVATIVE OF 3,5-DIIODO-O-[3-IODOPHENYL]-L-TYROSINE Russian patent published in 2019 - IPC C07C309/42 A61K31/198 

Abstract RU 2708244 C1

FIELD: chemistry.

SUBSTANCE: invention relates to a non-radioactive conjugate of 3,5-diiodo-O-[3-iodo-4-(sulphoxy)phenyl]-L-tyrosine (T3S) selected from the group consisting of: a) conjugate T3S-biotin of formula A'

b) conjugate T3S-HRP (horseradish peroxidase) and c) a chelating agent T3S-europium of formula V

.

EFFECT: technical result: obtaining novel conjugates of 3,5-diiodo-O-[3-iodo-4-(sulphooxy)phenyl]-L-tyrosine for use in non-radioactive immunoassay designed to determine T3S and quantitative determination of T3S.

3 cl, 3 dwg, 6 tbl, 6 ex

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RU 2 708 244 C1

Authors

Anelli, Pier Lucio

Argese, Maria

Boi, Valeria

Cavalieri, Livio

Galimberti, Laura

Gazzetto, Sonia

Lattuada, Luciano

Maisano, Federico

Rivolta, Giovanni

Vella, Fulvia

Dates

2019-12-05Published

2018-07-06Filed