FIELD: medicine, pharmaceutics.
SUBSTANCE: group of inventions refers to medicine. A therapeutic agent for corneal endothelial dysfunction containing (R)-(+)-N-(1H-pyrrolo[2,3-b]pyridin-4-yl)-4-(1-aminoethyl)benzamide <Y-39983> or its pharmacologically acceptable salt (compound (Ia)) as an active ingredient, an agent for corneal endothelial cell adhesion stimulation containing the compound (Ia), a corneal endothelial cell culture medium containing the agent for adhesion stimulation, a corneal graft for endothelial keratoplasty comprising corneal endothelial cells, a frame and the compound (Ia), and a method for producing a corneal endothelial preparation involving the stage of corneal endothelial cell culture with the use of the culture medium.
EFFECT: agent is used for the effective and comfortable treatment of the diseases involving the corneal endothelial cell damage accompanied by in vivo proliferation impairment.
21 cl, 17 dwg, 10 ex
| Title | Year | Author | Number |
|---|---|---|---|
| AGENT FOR PROMOTION OF CORNEAL ENDOTHELIOCYTE ADHESION | 2008 |
|
RU2474434C2 |
| NEW CORNEAL TREATMENT WITH LAMININ | 2015 |
|
RU2718062C2 |
| EXCITER OF NEURITES FORMATION | 2008 |
|
RU2442582C2 |
| EYE DROPS | 1997 |
|
RU2121825C1 |
| THERAPEUTIC AGENT FOR KERATOCONJUNCTIVE DISORDERS | 2013 |
|
RU2659203C2 |
| MEDICATION, METHOD OF OBTAINING MEDICATION, AND METHOD OF TREATMENT FOR CORNEA EDEMA AND OTHER EARLY BULLOUS KERATOPATHY MANIFESTATIONS | 2008 |
|
RU2357743C1 |
| SOLUTION TO STORE CORNEAL TISSUES INCLUDING HYALURONIC ACID | 1997 |
|
RU2184448C2 |
| TREATMENT OF ATHEROSCLEROSIS AND OTHER CARDIO-VASCULAR DISEASES | 1995 |
|
RU2235541C2 |
| USING LAMININ IN CORNEAL ENDOTHELIAL CELL CULTURE | 2014 |
|
RU2704984C1 |
| METHOD FOR OBTAINING A DONOR GRAFT OF DESCEMET'S MEMBRANE WITH AN ENDOTHELIAL LAYER | 2022 |
|
RU2786330C1 |
