METHOD FOR PRODUCING 2,3,7-TRIOXYJUGLONE (SPINOCHROME B) Russian patent published in 2015 - IPC A61K31/122 A61K35/56 

Abstract RU 2568604 C1

FIELD: medicine.

SUBSTANCE: raw material is sea urchin's (Strongylocentrotus intermedius) shell and spines, which are defrosted or separated from a preserving agent by decantation, washed in water, defatted by ethanol, dried, ground, demineralised by concentrated phosphoric acid and added with distilled water, extracted three times in ethanol; the produced extract is passed through a chitosan column; the column effluent is boiled off; the residue is dissolved in distilled water, filtered, passed through a polychrome-1 column; the column is washed with distilled water; the end product is eluted with an aqueous solution of ethanol, evaporated to dryness, dissolved in ethyl acetate; the end product is deposited by hexane, filtered and dried.

EFFECT: extending the range of biologically active substances produced by industrial processing of commercial sea urchins (S intermedius) that makes it possible to produce an individual compound - spinochrome B, which is an effective antioxidant and exhibits the antiallergic properties.

3 dwg, 1 ex

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RU 2 568 604 C1

Authors

Kupera Elena Vladimirovna

Artjukov Aleksandr Alekseevich

Rutskova Tat'Jana Anatol'Evna

Kochergina Tat'Jana Jur'Evna

Makhan'Kov Vjacheslav Valentinovich

Kozlovskaja Ehmma Pavlovna

Dates

2015-11-20Published

2014-12-11Filed