METHOD OF PRODUCING WATER-SOLUBLE SALT FORM OF ECHINOCHROME A, SUITABLE FOR USE IN PHARMACOLOGICAL AND FOOD INDUSTRY Russian patent published in 2019 - IPC C07C46/00 C07C50/32 

FIELD: technological processes.

SUBSTANCE: invention relates to a method of producing water-soluble monosodium salt of echinochrome A from sand dollar suitable for use in pharmacological and food industry. Method is characterized by that the freshly caught or defrosted raw material is preliminarily washed with drinking water, dried, poured with 96 % ethyl alcohol with addition of ascorbic acid at ratio of raw materials : ethyl alcohol : ascorbic acid 1:(1.0–1.2):(0.003–0.005) (kg : l : kg) and extracted at room temperature for 22–26 hours, then obtained extract is drained and evaporated, then the concentrated residue is diluted with distilled water and passed through the column with polychrome 1, then the pigment fractions are eluted with 40 % ethyl alcohol, the eluate is evaporated to dryness, then defatted raw material is subjected to double extraction with 96 % ethyl alcohol with addition of phosphoric acid at room temperature in ratio of raw materials : ethyl alcohol : phosphoric acid 1:(1.0–1.2):(0.002–0.005) (kg : l : kg) for 22–26 hours, then obtained extracts are drained, combined and evaporated, and the dry residue obtained at the extraction step is combined with the eluate concentrate and washed with distilled water. Further, the concentrate is dissolved in 1.0 % aqueous solution of sodium bicarbonate in ratio of concentrated residue : soda solution 1:(1.5–2.0) (kg : l), then obtained solution is centrifuged, residue is discarded, and obtained aqueous solution containing echinochrome A monosodium salt is dried on lyophilic or spray drier to produce target product.

EFFECT: disclosed method enables to obtain echinochrome A monosodium salt which is well soluble in water without loss of functional properties inherent in echinochrome A.

1 cl, 4 dwg, 2 ex