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2 568 841

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(51)

IPC

A61K31/4188(2006-01-01)

A61P25/08(2006-01-01)

(21) (22)

Application

2014137852/15, 2014-09-19

(24)

Start date

2014-09-19

(22)

Actual filing date

2014-09-19

(45)

Published

2015-11-20

(72)

Inventor

Spasov Aleksandr AlekseevichPetrov Vladimir IvanovichAnisimova Vera AlekseevnaMinkin Vladimir IsaakovichGrechko Olesja Jur'EvnaKalitin Konstantin Jur'Evich

(73)

Holder

Federal'Noe Gosudarstvennoe Avtonomnoe Obrazovatel'Noe Uchrezhdenie Vysshego Obrazovanija Federal'Nyj Universitet"Gosudarstvennoe Bjudzhetnoe Obrazovatel'Noe Uchrezhdenie Vysshego Professional'Nogo Obrazovanija Gosudarstvennyj Meditsinskij Universitet" Ministerstva Zdravookhranenija Rossijskoj Federatsii

ANTISPASMODIC MEDICATION Russian patent published in 2015 - IPC A61K31/4188 A61P25/08

Abstract RU 2568841 C1

FIELD: pharmacology.

SUBSTANCE: as compound, possessing antispasmodic activity claimed is dihydrochloride 9-dialkylaminoethyl-2-(4-chlorophenyl)imidazol[1,2-a]benzimidazole of general formula I where Ia NR₂= dimethylamino- Ib NR₂ = diethylamino-. Therapeutic index of dihydrochloride 9-dialkylaminoethyl-2-(4-chlorophenyl)imidazol[1,2-a]benzimidazole was in 10 times higher than of sodium valproate.

EFFECT: antispasmodic activity of compounds exceeding activity of sodium valproate has been identified.

2 cl, 3 tbl

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RU 2 568 841 C1

Authors

Spasov Aleksandr Alekseevich

Petrov Vladimir Ivanovich

Anisimova Vera Alekseevna

Minkin Vladimir Isaakovich

Grechko Olesja Jur'Evna

Kalitin Konstantin Jur'Evich

Dates

2015-11-20—Published

2014-09-19—Filed