FIELD: biotechnology.
SUBSTANCE: strain of cultivated hybrid animal cells Mus musculus is claimed - producer of monoclonal antibodies to an epitope as part of the antigen 200 kDa, exposed on the surface of microbial cells of the melioidosis pathogen (B. pseudomallei). The strain is deposited in the State collection of the pathogenic microorganisms and cell cultures "GKPM-Obolensk" under number H-40.
EFFECT: invention enables to obtain highly specific monoclonal antibodies suitable for the manufacture on their basis of the highly active diagnostic preparation for the MFA, specifically staining the microbial cells of virulent strains of melioidosis pathogen, which does not have the cross activity against the closely related opportunistic Burkholderia.
4 ex
| Title | Year | Author | Number |
|---|---|---|---|
| STRAIN OF CULTIVATED HYBRID ANIMAL CELLS MUS MUSCULUS L BPM VD-11 - PRODUCERS OF MONOCLONAL ANTIBODY 6A/G TO ANTIGEN 200 kDA OF MELIOIDOSIS PATHOGEN | 2014 |
|
RU2570634C1 |
| STRAIN OF CULTIVATED HYBRID CELLS OF ANIMAL Mus musculus Bpm Vd-8 - PRODUCER OF MONOCLONAL ANTIBODY 3C/A TO ANTIGEN 200 kDa OF PSEUDOCHOLERA ACTIVATOR | 2014 |
|
RU2555544C1 |
| STRAIN OF CULTURED HYBRID CELLS OF ANIMAL MUS MUSCULUS - A PRODUCER OF MONOCLONAL ANTIBODY RAISED TO THERMOSTABLE SURFACE ANTIGEN OF MELIODOSIS PATHOGEN | 1997 |
|
RU2116344C1 |
| STRAIN OF CULTIVATED HYBRID ANIMAL CELLS Mus musculus Bpm Vd-9 - PRODUCER OF MONOCLONAL ANTIBODY 5C/F/C TO ANTIGEN 200 kDa MELIOIDOSIS AGENT | 2014 |
|
RU2556803C1 |
| STRAIN OF CULTIVATED HYBRID ANIMAL CELLS MUS MUSCULUS L CCHFV VD-1-PRODUCER OF MONOCLONAL ANTIBODY 4G/B TO VIRUS OF CRIMEAN-CONGO HEMORRHAGIC FEVER (CCHF) | 2013 |
|
RU2535982C1 |
| STRAIN OF CULTURED HYBRID CELLS OF ANIMAL MUS MUSCULUS - PRODUCER OF MONOCLONAL ANTIBODIES TO THERMOSTABLE COMPONENT OF CAPSULE-LIKE SUBSTANCE OF MELIODOSIS PATHOGEN | 1997 |
|
RU2117042C1 |
| METHOD FOR ACCELERATED LINE IMMUNOELECTROPHORESIS FOR BURKHOLDERIA DIFFERENTIATION | 2012 |
|
RU2496112C1 |
| STRAIN OF CULTURED HYBRID CELLS OF ANIMAL MUS MUSCULUS - PRODUCER OF MONOCLONAL ANTIBODIES TO THERMOSTABLE ANTIGEN WHICH IS COMMON FOR GLANDERS AND MELIODOSIS PATHOGENS | 1997 |
|
RU2117043C1 |
| METHOD FOR OBTAINING THE ERYTHROCYTAL EQUINIA IMMUNOGLOBULIN MONOCLONAL DIAGNOSTICUM | 2017 |
|
RU2658434C1 |
| STRAIN OF HYBRID CULTURED CELLS OF ANIMALS MUS MUSCULUS L AS A PRODUCER OF MONOCLONAL ANTIBODIES TO THE PSEUDOMONAS PSEUDOMALEI ANTIBODIES, WHICH DO NOT REACT WITH MALLEUS INFECTION PATHOGENIC ORGANISM OF THE NEAREST RELATIONSHIP | 0 |
|
SU1740415A1 |
