METHOD FOR OPTIMISING SELECTING ANTIANGINAL THERAPY IN ISCHEMIC HEART DISEASE AND MICROVASCULAR ANGINA Russian patent published in 2015 - IPC A61B5/00 

FIELD: medicine.

SUBSTANCE: LDF and capillaroscopy initial parameters are determined. Recommended antianginal preparations are administered one by one for 3 days. Each following preparations is administered 5 excretion half-lives after the previous one, and each course is followed by determining the LDF parameters. That involves assessing: vascular reaction of skin microcirculation, functional health of tonus-forming mechanisms of blood flow modulation: endothelial - Ae, neurogenic - An and myogenic - Am, respiratory blood flow variations - Av, pulse blood flow variations - As, as well as the capillaroscopy parameters that is a pericapillary area - PA. The LDF and capillaroscopy (PA) initial parameters are compared to those obtained after the preparations tested are administered, and the most optimum preparation which makes the parameters Ae, An, Am and As normalise with Av≤0.08, PA = 105±15 is selected for a continuous therapy.

EFFECT: method enables providing higher therapeutic effectiveness and prevents disease recurrences in the patients with ischemic heart disease and microvascular angina.

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