FIELD: medicine.
SUBSTANCE: invention concerns a method for correcting individual's age-related pathological skin conditions; the method involves using patient's autogenous fibroblasts and administering them to the patient with material sampling and cell growth followed by patient's fibroblast culture recovery; the fibroblast culture is genetically analysed by detecting DNA sequence and activity of genes specified in a group consisting of TGFB1, TGFBR2, COL1A1, COL1A2, SOD1, SOD2, GPX1, GPX3, CLCA2; that is followed by carrying out a comparative analysis of the obtained results in relation to normal DNA sequences and normal expressions of respective genes and creating genetic constructs containing complementary DNA of those genes, activity of which is changed in a patients or DNA structure of which is irregular, and introducing these genetic constructs into the patient's fibroblast culture, and administering these modified autogenous fibroblasts into the patient.
EFFECT: reducing the clinical signs of skin ageing accompanied by positive progression of skin functional parameters.
8 cl, 16 ex, 13 dwg, 20 tbl
