LIPOSOMAL COMPOSITIONS APPLICABLE FOR DRUG DELIVERY Russian patent published in 2016 - IPC A61K9/127 A61K31/00 A61P35/00 

FIELD: medicine, pharmaceutics.

SUBSTANCE: group of inventions refers to pharmacology and medicine and concerns a composition representing a liposome in a medium having an internal cavity separated from the medium by means of a membrane comprising one or more lipids with the internal cavity of the liposome comprising a cationic antineoplastic therapeutic agent, as well as polyol or sugar polyanion-exchanged by means of at least two high-anionic functional groups; sugar represents monosaccharide or disaccharide, wherein the cationic agent and polyanion-exchanged polyol or polyanion-exchanged sugar are presented in the form of an acid or salt, as well as contained inside the liposome, wherein the composition represents a dosage form for parenteral administration, as well as concerns a method for encapsulating the cationic antineoplastic therapeutic agent in the liposome.

EFFECT: group of inventions provides the high-load effectiveness delivery of therapeutic agents to a site, wherein a pathological process is localised.

66 cl, 74 ex, 40 tbl, 47 dwg