FIELD: medicine.
SUBSTANCE: invention refers to an immunoliposomal form of a photosensitiser form on the basis of tetra-3-phenylthiophthalocianine aluminium hydroxyl which is used in photodynamic therapy of malignant tumours. The immunoliposomal form contains said photosensitiser (0.011 g), egg phosphatidylcholine (2.2 g), cholesterol (0.264 g), mPEG2000-DSPE [methoxy(polyethylene glycol-2000)] 1,2-distearoyl-sn-glycero-3-phosphatidylethanolamine-N (0.0528 g), (pNP-PEG3400-DOPE) 1,2-dioleoyl-sn-glycero-3-phosphatidylethanolamine-N-[n-nitrophenylcarbonyl (polyethylene glycol-3400)] (0.0176 g), triple-substituted sodium citrate (0.53 g) and anti-CD5 MCA (ICO-80) (anti-CD5 monoclonal antibodies) (0.00237 g).
EFFECT: high phototoxic effect.
3 dwg, 3 ex
| Title | Year | Author | Number |
|---|---|---|---|
| GRANZYME B DELIVERY METHOD TO MAMMALIAN CELLS | 2021 |
|
RU2796685C2 |
| COATING FOR AN INTRALUMINAL DIVERGENT CATHETER, PROVIDING CONTACT DELIVERY OF MICRORESERVOIRS WITH A DRUG PREPARATION | 2015 |
|
RU2721655C2 |
| COATING FOR INTRALUMINAL EXPANDING CATHETER, PROVIDING CONTACT TRANSFER OF MICRORESERVOIRS WITH MEDICINAL PRODUCTS | 2019 |
|
RU2820776C2 |
| METHOD FOR OBTAINING SUPRAMOLECULAR PLATINUM COMPOUNDS | 2016 |
|
RU2795256C2 |
| BINARY IMMUNOLIPOSOMAL NANOSYSTEM OF TARGETED DELIVERY TO CONNEXIN -43 POSITIVE TUMOUR CELLS | 2009 |
|
RU2422154C2 |
| LIPOSOMAL COMPOSITIONS CONTAINING SLIGHTLY ACIDIC DRUGS, AND THEIR USE | 2018 |
|
RU2778886C2 |
| LIPOSOMAL COMPOSITIONS USED FOR DRUG DELIVERY | 2015 |
|
RU2757110C2 |
| COMPOUNDS FOR TARGETED DRUG DELIVERY AND ENHANCING siRNA ACTIVITY | 2012 |
|
RU2769872C2 |
| COMPOUNDS FOR TARGETED DELIVERY OF MEDICINE AND ENHANCED SIPHK ACTIVITY | 2012 |
|
RU2632888C2 |
| METHODS TO REDUCE COMPLICATIONS FROM INTRA-ARTICULAR STEROID | 2019 |
|
RU2806023C2 |
