FIELD: chemistry.
SUBSTANCE: invention relates to biologically active peptide complexes with immunomodulating and antiviral activity. The disclosed peptide complexes have a three-dimensional structure 
wherein X1 is absent or contains at least 1 amino acid; R1 and R2 are peptide chains which contain amino acid residues, His or Cys, capable of reacting with transition metal ions, wherein R1 contains up to 5 amino acid residues or is absent; R2 contains up to 3 amino acid residues or is absent.
EFFECT: peptide complexes rich in histidine and, primarily alloferon peptides with Zn ions, enable to produce preparations with a directed mechanism of action and enable their design in accordance with the understanding of the structure of the medicinal target.
3 cl, 7 dwg, 2 tbl, 6 ex
| Title | Year | Author | Number |
|---|---|---|---|
| ANTI-TUMOR AND ANTIVIRAL PEPTIDES | 2004 |
|
RU2267496C2 |
| BIOLOGICALLY ACTIVE PEPTIDES | 2013 |
|
RU2575069C2 |
| OXYNTOMODULIN COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THEREOF, METHOD OF TREATING AND PREVENTING OBESITY AND COMORBIDITIES (VERSIONS) AND MEDICINE (VERSIONS) | 2006 |
|
RU2485135C2 |
| HYBRID PROTEIN CONTAINING FRAGMENTS OF FLUORESCENT PROTEINS AND ITS APPLICATION | 2020 |
|
RU2801248C2 |
| METHODS FOR QUANTITATIVE DETERMINATION OF POLYPEPTIDES | 2019 |
|
RU2782464C2 |
| ANTIBODIES BINDING TO HLA-A2/WT1 | 2018 |
|
RU2815176C2 |
| PROTEIN COMPOSITIONS AGAINST VEGF AND METHODS FOR THEIR PRODUCTION | 2020 |
|
RU2795973C1 |
| NOVEL METHODS OF ENZYME-MEDIATED CONJUGATION OF POLYPEPTIDES USING SORTASE | 2015 |
|
RU2714963C2 |
| PHARMACEUTICAL COMPOSITIONS CONTAINING PEPTIDE VERSIONS, AND METHODS OF USING THEM | 2015 |
|
RU2729161C2 |
| ENZYMATIC ONE-REACTION REACTION OF POLYPEPTIDES DOUBLE CONJUGATION IN ONE STEP USING SORTASE | 2015 |
|
RU2711364C2 |
