FIELD: medicine, pharmaceutics.
SUBSTANCE: invention refers to heterocyclic compounds of formula Ib and its pharmaceutically acceptable salts, wherein X, Y and Z represent CH; o is equal to 1; n is equal to 0; m is equal to 1 or 2; A represents C=O; W represents NH; in each specific case, R2 is independently specified in a group consisting of C1-C10 alkyl; in each specific case, R3 is independently specified in a group consisting of halogen, C1-C10 alkyl optionally substituted by halogen; OR6, -NO2, heteroaryl representing pyridyl; in each specific case, R6 is independently specified in a group consisting of C1-C10 alkyl and C1-C10 halogenalkyl; R10 represents a fragment specified in a group consisting of 
wherein m' is equal to 0, 1, 2, 3 or 4; in each specific case, R11 is independently specified in a group consisting of hydrogen and C1-C10 alkyl; in each specific case, R12 is independently specified in a group consisting of hydrogen, C1-C10 alkyl optionally substituted by OR8 group, heterocyclyl representing morpholinyl, or by hydroxyl; C3-C10 cycloalkyl, C1-C10 halogenalkyl, hydroxyl, -OR14, C(O)R14, -C(O)N(R14)2, phenyl optionally substituted by halogen, -N(R8)C(O)R8 group or OR8 group; benzyl optionally substituted by halogen or OR8 group; in each specific case, R14 is independently specified in a group consisting of hydrogen, C1-C8 alkyl; phenyl optionally substituted by halogen, C1-C3 halogenalkyl or OR8 group, benzyl optionally substituted by halogen; in each specific case, R8 is independently specified in a group consisting of hydrogen, C1-C10 alkyl, C1-C3 halogenalkyl, C3-C7 cycloalkyl, phenyl substituted by halogen or OR8 group. The invention also refers to specific compounds, using the above compounds, a pharmaceutical composition based on the compound of formula 
EFFECT: activity of certain known compounds has been examined, and the new compounds possessing inhibitory activity on mycobacterial growth have been produced.
10 cl, 3 dwg, 2 tbl, 3 ex
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