FIELD: medicine.
SUBSTANCE: group of inventions refers to compositions in the form an aqueous solution for injections, having a pH value in the range from 6.0 to 8.0, and containing at least: a) basal insulin the isoelectric point pI of which falls within 5.8 and 8.5, and b) dextran having carboxyl-containing charge carrier radicals and hydrophobic radicals as substitutes.
EFFECT: retaining the properties of basal insulin, while maintaining its post-injection long-acting profile in a physiological environment.
38 cl, 12 dwg, 16 tbl, 77 ex
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Authors
Dates
2016-03-27—Published
2012-08-09—Filed