FIELD: medicine, pharmaceutics.
SUBSTANCE: present invention refers to new biologically compatible polymers of dextran, namely functionalised dextran of general formula I. Dextran is functionalised by at least one residue of hydrophobic alpha-amino acid with said alpha-amino acid is cross-linked or coupled with dextran by a coupling branch R and one function F which have the values specified in the description. A residue of hydrophobic alpha-amino acid means an interaction product of amine of amino acid and acid of the coupling branch with dextran being amphiphilic at neutral pH, while a polymerisation degree of dextran makes 10 to 10000. According to one version of the implementation, hydrophobic amino acid is specified in phenylalanine, leucine, isoleucine and valine and their alcohol, amide or decarboxylated derivatives.
EFFECT: invention also refers to a pharmaceutical composition containing one of dextrans under the invention.
12 cl, 6 ex
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